Immune Globulin, Hepatitis B in Pregnancy and Breastfeeding
Fetal Risk Summary
Hepatitis B immune globulin is used to provide passive immunity following exposure to hepatitis B. When hepatitis B occurs during pregnancy, an increased rate of abortion and prematurity may be observed (1). No risk to the fetus from the immune globulin has been reported (1,2). The American College of Obstetricians and Gynecologists Technical Bulletin No. 160 recommends use of hepatitis B immune globulin in pregnancy for postexposure prophylaxis (1).
Breast Feeding Summary
No data are available.
- American College of Obstetricians and Gynecologists. Immunization during pregnancy. Technical Bulletin. No. 160, October 1991.
Amstey MS. Vaccination in pregnancy. Clin Obstet Gynaecol 1983;10:1322.