Urea in Pregnancy and Breastfeeding
Risk Factor: C
Class: Diuretics
Fetal Risk Summary
Urea is an osmotic diuretic that is used primarily to treat cerebral edema. Topical formulations for skin disorders are also available. No reports of its use in pregnancy following IV, oral, or topical administration have been located. Urea, given by intraamniotic injection, has been used for the induction of abortion (1).
Breast Feeding Summary
No data are available.
References
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Ware A, ed. Martindale: The Extra Pharmacopoeia. 27th ed. London: The Pharmaceutical Press, 1977:572.
