Vaccine, Meningococcal in Pregnancy and Breastfeeding

Risk Factor: CM
Class: Serums, toxoids, and vaccines / Vaccines

Contents of this page:
Fetal Risk Summary
Breast Feeding Summary
References
Questions and Answers

Fetal Risk Summary

Meningococcal polysaccharide vaccine is a killed bacteria (cell wall) vaccine (1,2). Animal reproduction studies have not been conducted with the vaccine (1).

The risk to the fetus from vaccination during pregnancy is unknown. In one study, vaccination resulted in transfer of maternal antibodies to the fetus, but the transfer was irregular and was not dependent on maternal titer or the period in pregnancy when vaccination occurred (3).

A 1998 study evaluated the pregnancy outcomes of 34 women who received meningococcal vaccine during pregnancy (4). The trimesters of exposures were 4 (11.8%) in the 1st, 17 (50.0%) in the 2nd, and 13 (38.2%) in the 3rd. There were 34 singleton deliveries with a mean follow-up of the offspring of 13.2 months (range 124 months). Excluding one congenital malformation, there was no increase in the observed unusual birth events compared with the expected rates. In fact, there were significantly fewer cases of newborn cardiac murmurs and physiologic jaundice in offspring of vaccinated mothers. One birth defect observed in an infant of a mother vaccinated at 33 weeks' gestation was consistent with the oromandibular limb hypogenesis spectrum (Charlie M syndrome) (expected frequency <0.00002%). This pattern of defects would probably have occurred very early in gestation (4). The cause of Charlie M syndrome is unknown; it has not yet been identified as a genetic defect and it has not been associated with teratogens. All of the infants had normal growth and development in the follow-up period (4).

The use of the vaccine during pregnancy is controversial (5). Although an earlier publication of the American College of Obstetricians and Gynecologists recommended that the vaccine be used during pregnancy only when the risk of maternal infection is high (6), the current 1991 version, Technical Bulletin No. 160, does not discuss this vaccine (7).

In a 1996 study, 75 mothers received meningococcal vaccine in the last trimester of pregnancy (8). No adverse effects in the newborns attributable to the vaccine were observed.

Breast Feeding Summary

No data are available.

References

  1. Product information. Menomune -A/C/Y/W-135. Aventis Pasteur, 2001.
  2. Amstey MS. Vaccination in pregnancy. Clin Obstet Gynaecol 1983;10:1322.
  3. Carvalho ADA, Giampaglia CMS, Kimura H, Pereira OADC, Farhat CK, Neves JC, Prandini R, Carvalho EDS, Zarvos AM. Maternal and infant antibody response to meningococcal vaccination in pregnancy. Lancet 1977;2:80911.
  4. Letson GW, Little JR, Ottman J, Miller GL. Meningococcal vaccine in pregnancy: an assessment of infant risk. Pediatr Infect Dis 1998;17:2613.
  5. Linder N, Ohel G. In utero vaccination. Clin Perinatol 1994;21:66374.
  6. American College of Obstetricians and Gynecologists. Technical Bulletin. No. 64, May 1982.
  7. American College of Obstetricians and Gynecologists. Immunization during pregnancy. Technical Bulletin. No. 160, October 1991.
  8. O'Dempsey TJD, McArdle T, Ceesay SJ, Banya WAS, Demba E, Secka O, Leinonen M, Kayhty H, Francis N, Greenwood BM. Immunization with a pneumococcal capsular polysaccharide vaccine during pregnancy. Vaccine 1996;14:96370.

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Questions and Answers

What are some dangerous side effects of the meningococcal vaccine?, To go to school, my 11 year old brother needs it, but he is very very small and my mom was wondering if that puts him at risk for any side effects.

Here is the detailed vaccine information that comes with each vaccine. It is given to doctors, but not patients. It takes awhile to read, but it's a big deal to get injected with a drug, so make sure your mom is fully informed.

There are two brands:

Menactra http://www.vaccineshoppe.com/image.cfm?p...

Menomune: http://www.vaccineshoppe.com/US_PDF/Meno... (notice the multi-dose vial contains 25 mcg of mercury per dose, which is a HUGE amount of mercury).

It's really unbelievable that in the safety study for Menactra, the control group was a group of people who received Menomune. The control group should have received a placebo!!! But the pharmaceutical company knew that if they gave the control group a placebo, it would show a lot more adverse effects of Menactra that way. If you do in-depth research on vaccines you'll find that the whole system is corrupt and that vaccines are A LOT more dangerous than the general public believes.

It says right in the vaccine inserts that the vaccines increase the risk of Guillain-Barre Syndrome, which is a very serious illness.

Here is the vaccine exemption information for schools. Your brother does NOT need the vaccine.

United States: http://mothering.com/discussions/showthr...

Canada: http://vran.org/legal/forms.htm

Why is the Meningococcal vaccine part of immunization at 12 months in Canada but not until 12 years in the USA, In Canada, the vaccine is for Serogroup C only and in the USA its for Serogroup A,C,Y & W135. Why is it ok to vaccinate such young babies in Canada but not in the US and why is only one type of the strain offered in Canada and four in the USA?

The one that's being offered in the States is fairly new to the market. The Canadian FDA version has not ok'd it to be used in Canada yet (we often lag behind by years at a time with introducing medical options in comparison with the States). We also follow a different immunization schedule than the States. Every country is different.

Is meningococcal polysaccharide vaccine safe during pregnancy?,

You need to ask your doctor.
Everything has risks---but this might protect your baby against something you have no anti-bodies against.

Good luck.

Meningococcal vaccine? Where to get it? South Mississippi.?, I am required to get a Meningococcal vaccine before August 1.
I can't find a provider that administers it to adults. The health department does, but only takes cash and I am not paying $141 for something my insurance covers in full! Does anyone know where to get one in Coastal Mississippi?

Join the army, they gave the vaccine to me and i did not even want it or need it.

Allergic reaction to meningococcal meningitis vaccine?, I got this vaccination and two days later my whole upper arm swelled up. It is now three days since I got the shot and it is still bright red, very hot and really swollen.

Are these normal side affects of this vaccine?

Normal reactions: It is common to get swelling, redness or pain where the shot was given. These symptoms usually last for 1-2 days. An infection is rare, but possible.

To check if you have an infection - Do you have a fever? or shivering chills? If not, try using a cold pack (or a bag of peas) and see if that helps. It should slowly improve. If it is not improving, you might want to see a GP.

You can also call the National Immunisation Hotline - 1800 671 811 or visit http://www.immunise.health.gov.au/ (I assume you're Australian)

Hope you feel better soon!

how often should a reson get the Meningococcal Vaccine?,

NEVER!

Do NOT get vaccinated.

A vaccinated person is MORE likely to get a disease than a non-vaccinated person. The whole theory of vaccination is flawed. It causes a weakening of the immune system thus making those who are innoculated more susceptible to disease.
There are so many awful side effects to vaccination that it should be considered extremely dangerous.
Just sit back and think for a while.
Is there any sense in injecting a disease directly into the bloodstream.
We have been subjected to an awful mind control program to enable the drug manufacturers to make a fortune.

The Vaccination Hoax
http://www.whale.to/b/hoax1.html


If you go to the vaccination liberation web page, at
http://www.vaclib.org/exemption.htm
You will find all the forms necessary to provide exemption for your child.

If you want to study the history of vaccination, see
http://dgwa1.fortunecity.com/body/vaccin...

I recently had the meningococcal vaccine. What are some of the side effects?, I received the meningococcal vaccine a little over 48 hours ago. Within the first 24 hours I had a fever and chills and was feeling weak. My arm also began to become sore. I know all of these side effects are normal.
The next day I seemed to have lost the fever and weakness, but now the lymph nodes in my armpit are swollen and sore. I noticed that my neck is also a little sore and stiff. It's fine unless I try to turn it to either side.

I was just asking some of you guys' opinions, because I know the side effects of this vaccine can become potentially fatal. I'm not sure what to do because the symptoms I have seem to be more severe than normal, but I'm not sure where exactly they fit..

That's normal, just more severe than usual ... your lymph nodes are where your body produces antibodies, and the swelling means they are in full production. The nodes in your armpits and neck, being closest to the shot, will react the most strongly.

Some people's immune systems go a bit hyperactive.

Take a couple of ibuprofen and apply ice packs to the armpit.

Why is it that the vaccine for meningococcal (neis vac C) is ineffective when given before the infant's second, birthday?

CAUTION!

Vaccines aren't exactly wht you would consider safe or for the best of your child's or anyone's health!

please read if you are really concerned:http://www.soilandhealth.org/02/0201hygl...

then you can properly make your own decision on whether Vaccines are the answer.

Does the meningococcal vaccine hurt?, Does this vaccine hurt a lot? and where is it given? (ex: upper arm)

It is given in the upper arm. It doesnt hurt anymore than other shots. It may be a little sore the next day. It also made me a little achy all over (but all shots make me feel crumby the next day).

meningococcal Meningitis Vaccine?, I recently got a vaccine for Meningitis, A day later, I have mild pressure in my forehead, and I feel generally sick. I don't have a stiff neck so I don't think I have Meningitis. Is this kind of reaction normal, how long does it last?

It's common to have fever and a mild sick feeling after a vaccine shot, which usually lasts only for a day after the vaccination.

If your headache is persistent on the 2nd day, see your MD because meningococcal vaccine has rarely been known to cause neurological problems in people who have had any previous neurological illnesses such as Guillain-Barre syndrome or seizures.